Why We Pair PDRN and Exosomes With Microneedling — And Why the Order Matters
Microneedling treatments like SkinPen® and Potenza® RF Microneedling are powerful tools for improving skin texture, firmness, and overall quality. By creating controlled micro-injuries, these treatments stimulate your skin’s natural repair process — encouraging collagen and elastin production from within.
At Pure Lux Medspa in Edina / Minneapolis, we take this process one step further by thoughtfully pairing microneedling with regenerative ingredients like PDRN and Exosomes. Just as important as what we use is WHEN we use it.
Understanding How Skin Heals After Microneedling
When the skin is microneedled, it goes through distinct phases of healing:
Initial repair and recovery
Collagen rebuilding
Strengthening and refinement
Supporting each phase properly helps ensure the skin heals in a healthier, stronger way — and leads to better long-term results.
This is why we don’t treat every microneedling session the same.
What PDRN Does for the Skin
PDRN supports the skin’s natural repair process, making it especially beneficial early in a microneedling series.
In simple terms, PDRN helps:
Support proper tissue repair
Strengthen weakened or thinning skin
Encourage healthier collagen formation
Calm inflammation and improve recovery
Think of PDRN as helping the skin rebuild correctly, so the collagen created is strong and supportive — not rushed or stressed.
What Exosomes Do for the Skin
Exosomes work differently. Instead of focusing on repair, exosomes help the skin use its repair tools more efficientlyonce healing is already underway.
Exosomes help:
Enhance how the skin responds to treatment
Improve overall skin quality and texture
Support more refined, visible results
Optimize collagen and elastin activity
Rather than forcing change, exosomes help the skin maximize the work it’s already doing.
Why We Recommend 2 Treatments With PDRN and 1 With Exosomes
When completing a series of three SkinPen® or Potenza® RF Microneedling treatments, we often recommend:
Treatments 1 & 2: Microneedling with PDRN
Treatment 3: Microneedling with Exosomes
Here’s why this approach works so well:
Treatments 1 & 2: Building a Strong Foundation
After the first two treatments:
The skin is actively repairing
Collagen production is increasing
The skin barrier is rebuilding
Using PDRN during this phase helps ensure the skin heals in a healthy, supported way — setting the foundation for long-term improvement.
Treatment 3: Refining and Enhancing Results
By the third treatment:
The skin is stronger and more resilient
Collagen production is already active
The skin is more responsive
This is the ideal time to introduce exosomes, which help refine results and improve overall skin quality — enhancing what has already been built.
Why This Combination Delivers Better Results
Rather than doing the same add-on at every visit, this approach respects how the skin actually heals.
In simple terms:
PDRN helps rebuild and strengthen the skin
Exosomes help the skin get more out of that strength
Together, they support a more balanced, natural result — without over-stimulating or overwhelming the skin.
Who This Approach Is Best For
This protocol is ideal for clients who:
Want to improve skin texture and firmness
Are addressing early to moderate signs of aging
Prefer a thoughtful, non-aggressive approach
Want long-term skin health, not just short-term results
Your provider will always customize recommendations based on your skin, goals, and treatment plan.
Microneedling With PDRN & Exosomes in Edina & Minneapolis
At Pure Lux Medspa, we believe better results come from strategic treatment planning, not just stronger products.
If you’re searching for SkinPen® or Potenza® RF Microneedling with PDRN or Exosomes in Edina or Minneapolis, our team is here to guide you through a personalized approach designed to support healthier, stronger skin.
📍 Pure Lux Medspa | Edina / Minneapolis, MN
✨ Schedule your microneedling consultation today and experience results that are built — not rushed.